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Single cell sequencing sheds light on why cancers form in sp
While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms. Instead, tumors arise when a mutation happens in a p
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单细胞测序揭示了癌症在特定细胞类型中形成的
 虽然我们体内的许多细胞可以积累致癌突变,但这些事件中的大多数不会导致肿瘤形成,因为这些异常细胞被防御机制消除。相反,当突变发生在对其特异性敏感的特定细胞类型中时
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单细胞RNA测序方法的比较分析
单细胞mRNA测序(scRNA-seq)允许分析异质细胞群,提供解决各种生物和医学问题的令人兴奋的可能性。最近开发了一系列方法,因此有必要系统地比较它们的灵敏度,准确度,精度和成本效
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Comparative analysis of single-cell RNA-sequencing methods
Single-cell mRNA sequencing (scRNA-seq) allows to profile heterogeneous cell populations, offering exciting possibilities to tackle a variety of biological and medical questions. A range of methods has been recently developed, making it nece
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Single-cell RNA-Seq of cells in the early human placenta may
To treat and prevent pregnancy-related disorders, researchers must understand not only what can go wrong, but when. Complications, such as preeclampsia and pre-term birth, often occur in the second or third trimester, and most research to da
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早期人胎盘中的单细胞RNA-Seq细胞可以揭示问题怀
为了治疗和预防与妊娠有关的疾病,研究人员不仅要了解可能出现的问题,还要了解何时出错。并发症如先兆子痫和早产,通常发生在妊娠中期或妊娠晚期,迄今为止的大多数研究都集
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用于高通量单细胞RNA测序的惯性有序辅助液滴微
单细胞RNA-seq揭示了细胞群中固有的细胞异质性,这在许多临床和研究应用中非常重要。
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Inertial-ordering-assisted droplet microfluidics for high-th
Single-cell RNA-seq reveals the cellular heterogeneity inherent in the population of cells, which is very important in many clinical and research applications. Recent advances in droplet microfluidics have achieved the automatic isolation, l
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